Ecolla™ PLLA Collagen Stimulator 365mg

Ecolla™ PLLA is an advanced poly-L-lactic acid (PLLA) collagen-stimulating injectable designed to support the skin’s natural collagen production and progressively restore facial volume and structure. Unlike conventional hyaluronic acid fillers that provide volume primarily through the presence of a gel, Ecolla works as a biostimulator, encouraging gradual collagen formation within the treated area.

The formulation contains 150mg of PLLA, together with 90mg carboxymethylcellulose (CMC) and 125mg mannitol, supplied as a 365mg lyophilised powder in a single vial. The PLLA particles are designed to stimulate collagenesis in the subcutaneous layer, producing progressive and natural-looking improvement in volume, skin structure and facial contours.

Key Benefits of Ecolla™ PLLA

• Stimulates natural collagen production
• Helps restore facial volume lost through ageing
• Improves the appearance of deep lines and facial folds
• Supports improved skin structure and elasticity
• Helps improve facial contour and definition
• Provides gradual, natural-looking volumisation
• Uses a biodegradable PLLA polymer
• Designed for long-lasting collagen stimulation
• Suitable for professional aesthetic treatment protocols

How Does Ecolla™ PLLA Work?

Ecolla contains poly-L-lactic acid, a biodegradable synthetic polymer that acts as a collagen stimulator. PLLA stimulates collagen production within the deeper tissue layers. As collagen develops progressively, the treated area can gain improved structural support and volume.

This gradual mechanism differentiates Ecolla from traditional HA dermal fillers, making it suitable for patients seeking a more progressive approach to facial rejuvenation rather than an immediate volumising effect.

Ecolla™ PLLA Treatment Areas

Ecolla may be used by appropriately trained practitioners to address facial volume loss, deep wrinkles and contour changes. Manufacturer information indicates applications including:

• Cheeks and mid-face
• Nasolabial folds
• Marionette lines
• Temples
• Chin
• Jawline and facial contours
• Facial lipoatrophy
• Facial contour deformities

Treatment suitability and precise injection sites should always be determined following an individual facial assessment by a qualified practitioner.

Gradual, Long-Lasting Results

Ecolla is designed to produce progressive collagen stimulation rather than an immediate filler effect. Manufacturer information states that the volume effect can last up to 24 months, while individual results can vary depending on the patient’s anatomy, treatment plan and response to collagen stimulation. The manufacturer’s brochure describes a course of three treatments at 4–6 week intervals.

Product Specifications

The composition and packaging above are based on the manufacturer’s Ecolla brochure.

Ecolla™ PLLA vs Traditional Dermal Fillers

Ecolla offers a different approach to facial rejuvenation by focusing on collagen stimulation and progressive structural improvement. Rather than relying solely on an injected gel to create volume, PLLA stimulates the body’s own collagen production, helping restore volume and support over time.

For professional use only. Ecolla™ PLLA should be prepared and administered by an appropriately trained and qualified practitioner in accordance with the manufacturer’s current instructions for use and applicable UK requirements.