Nucleofill Medium | Polynucleotide Skin Booster

Nucleofill Medium, formerly known as Nucleofill 20, is a professional polynucleotide (PN) skin-rejuvenation treatment designed to support the skin’s natural regenerative processes and improve overall skin quality. Its polynucleotide-based formulation provides a biorevitalising approach to skin ageing, helping support hydration, elasticity, firmness and tissue regeneration.

Polynucleotides work by supporting fibroblast activity, helping promote the production of collagen and elastin within the skin. This can contribute to progressive improvements in skin structure, elasticity and the visible signs of ageing.

Key Benefits

• Supports natural skin regeneration
• Helps stimulate fibroblast activity
• Supports collagen and elastin production
• Helps improve skin firmness and elasticity
• Supports improved skin texture and quality
• Provides antioxidant and anti-inflammatory properties
• Helps improve the appearance of ageing and tired-looking skin
• Suitable for a wide range of skin types
• Can be used across multiple areas of the face and body

How Nucleofill® Medium Works

Nucleofill Medium uses polynucleotides to support the skin’s natural repair and remodelling processes. Following professional administration, the PN formulation helps create an environment that supports fibroblast activity and extracellular matrix regeneration.

As collagen and elastin production are supported, the skin can progressively appear firmer, smoother and more elastic, helping to improve overall skin quality without relying on conventional volumising filler.

Treatment Areas

Nucleofill Medium is suitable for professional treatment of several areas affected by skin ageing, loss of elasticity or reduced skin quality, including:

• Face
• Neck
• Hands
• Abdomen

Its versatility makes it suitable for both facial rejuvenation and selected body skin-quality treatments.

Suitable for All Skin Types

Nucleofill Medium can be incorporated into personalised aesthetic treatment programmes for all skin types. It may be particularly beneficial for skin showing signs of dehydration, reduced elasticity, fine lines, laxity or general age-related deterioration.

Treatment suitability, technique and treatment frequency should always be determined following an individual assessment by an appropriately qualified practitioner.

Product Specifications

For professional use only. Nucleofill® Medium should be administered by an appropriately qualified and trained practitioner in accordance with the manufacturer’s current Instructions for Use and applicable UK requirements.