Plinest 2ml Polynucleotide Skin Booster

Plinest 2ml is a professional injectable polynucleotide skin rejuvenation treatment developed by Mastelli. It contains highly purified Polynucleotides HPT™ (PN-HPT™), designed to support skin regeneration, improve skin quality and promote a healthier, more youthful-looking appearance.

Plinest is formulated as a sterile, non-pyrogenic and viscoelastic polynucleotide gel for intradermal injection. The treatment is primarily focused on improving skin quality rather than providing the volumising effect associated with traditional dermal fillers.

Key Benefits

• Supports natural skin regeneration
• Helps improve skin hydration and suppleness
• Supports fibroblast activity
• Helps improve collagen and extracellular matrix production
• Improves the appearance of skin elasticity and firmness
• Helps refine skin texture and overall skin quality
• Supports a smoother, more radiant complexion
• Can be incorporated into skin-priming and rejuvenation protocols
• Suitable for addressing areas with higher fibrous content, including certain scars

PN-HPT™ Technology

Plinest uses Polynucleotides HPT™, produced using Mastelli’s High Purification Technology. The highly purified polynucleotide formulation is designed for intradermal use and supports the skin’s natural regenerative processes.

Polynucleotides provide a supportive environment for fibroblast activity and extracellular matrix remodelling, helping improve the structural quality and appearance of ageing or compromised skin.

Treatment Areas

Plinest 2ml is designed for professional treatment of:

• Face
• Neck
• Décolletage

It may also be incorporated into personalised protocols for areas where improved skin quality and remodelling are required, including skin with a higher fibrous component such as certain acne scars.

Skin Priming & Rejuvenation

Plinest can be used as a standalone skin rejuvenation treatment or as part of a broader aesthetic treatment plan. Manufacturer information describes PN-HPT™ as a skin-priming treatment, which may complement procedures such as laser, radiofrequency, chemical peels, microneedling and dermal filler treatments.

Product Specifications

Mastelli’s product information confirms Plinest as a 2ml pre-filled polynucleotide gel supplied with two 30G ½ needles.

For professional use only. Plinest® should be administered by an appropriately qualified and trained practitioner in accordance with the manufacturer’s current Instructions for Use and applicable UK requirements.